Table 5 Association of MTL metabolism with cognitive fluctuation, RBD, and visual hallucinations

AD spectrum

Left amygdala

1.45 (1.08 ~ 1.98)

0.015

0.82 (0.56 ~ 1.21)

0.325

1.28 (0.79 ~ 2.10)

0.315

Right amygdala

1.50 (1.10 ~ 2.07)

0.013

0.80 (0.53 ~ 1.21)

0.292

1.07 (0.63 ~ 1.83)

0.797

Left hippocampus

1.25 (0.92 ~ 1.71)

0.161

0.83 (0.57 ~ 1.24)

0.359

1.08 (0.65 ~ 1.84)

0.785

Right hippocampus

1.47 (1.06 ~ 2.08)

0.024

0.85 (0.55 ~ 1.32)

0.472

1.01 (0.58 ~ 1.76)

0.978

Left entorhinal cortex

1.10 (0.85 ~ 1.44)

0.456

0.88 (0.62 ~ 1.24)

0.454

0.98 (0.63 ~ 1.54)

0.922

Right entorhinal cortex

1.20 (0.88 ~ 1.64)

0.257

0.96 (0.63 ~ 1.45)

0.831

1.00 (0.58 ~ 1.74)

0.999

DLB spectrum

Left amygdala

1.23 (0.91 ~ 1.67)

0.188

0.95 (0.7 ~ 1.28)

0.745

1.77 (1.24 ~ 2.57)

0.002

Right amygdala

1.34 (0.98 ~ 1.85)

0.071

0.87 (0.64 ~ 1.19)

0.396

1.71 (1.18 ~ 2.51)

0.005

Left hippocampus

1.01 (0.72 ~ 1.42)

0.940

1.01 (0.72 ~ 1.43)

0.942

1.61 (1.08 ~ 2.45)

0.022

Right hippocampus

1.32 (0.94 ~ 1.88)

0.114

0.95 (0.67 ~ 1.34)

0.758

1.36 (0.90 ~ 2.08)

0.147

Left entorhinal cortex

0.97 (0.73 ~ 1.28)

0.817

1.07 (0.81 ~ 1.43)

0.630

1.38 (0.99 ~ 1.95)

0.062

Right entorhinal cortex

1.18 (0.85 ~ 1.63)

0.327

1.02 (0.74 ~ 1.41)

0.912

1.59 (1.08 ~ 2.39)

0.022

Disease group

Left amygdala

1.45 (1.16 ~ 1.82)

0.001

0.99 (0.76 ~ 1.29)

0.932

1.97 (1.39 ~ 2.85)

< 0.001

Right amygdala

1.45 (1.15 ~ 1.85)

0.002

0.94 (0.71 ~ 1.24)

0.643

1.90 (1.31 ~ 2.78)

0.001

Left hippocampus

1.54 (1.21 ~ 1.97)

0.001

1.11 (0.84 ~ 1.49)

0.468

1.92 (1.30 ~ 2.87)

0.001

Right hippocampus

1.76 (1.36 ~ 2.31)

< 0.001

1.09 (0.81 ~ 1.47)

0.579

1.62 (1.10 ~ 2.42)

0.016

Left entorhinal cortex

1.31 (1.07 ~ 1.61)

0.009

1.15 (0.89 ~ 1.48)

0.286

1.57 (1.14 ~ 2.20)

0.007

Right entorhinal cortex

1.42 (1.13 ~ 1.80)

0.003

1.11 (0.83 ~ 1.48)

0.489

1.77 (1.21 ~ 2.62)

0.004